Konstanze F. Winklhofer : rechercher sur Z-Library

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1

Synthesis of a GPI anchor module suitable for protein post-translational modification

Miria C. Schumacher, Ulrike Resenberger, Ralf P. Seidel, Christian F. W. Becker, Konstanze F. Winklhofer, Dieter Oesterhelt, Jörg Tatzelt, Martin Engelhard

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 805 KB

english, 2010

2

Folding and misfolding of the prion protein in the secretory pathway

Tatzelt, Jörg, Winklhofer, Konstanze F

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 281 KB

english, 2004

3

The parkin protein as a therapeutic target in Parkinson's disease

Winklhofer, Konstanze F

Journal:

Expert Opinion on Therapeutic Targets

Année:

2007

Langue:

english

Fichier:

PDF, 228 KB

english, 2007

4

Inhibition of scrapie prion propagation

Jörg Tatzelt, Konstanze F. Winklhofer

Journal:

Gene Function & Disease

Année:

2001

Langue:

english

Fichier:

PDF, 615 KB

english, 2001

5

Semisynthetic Murine Prion Protein Equipped with a GPI Anchor Mimic Incorporates into Cellular Membranes

Diana Olschewski, Ralf Seidel, Margit Miesbauer, Angelika S. Rambold, Dieter Oesterhelt, Konstanze F. Winklhofer, Jörg Tatzelt, Martin Engelhard, Christian F.W. Becker

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

6

Inhibition of Complex Glycosylation Increases the Formation of PrPsc

Konstanze F. Winklhofer, Ulrich Heller, Anja Reintjes, Jörg Tatzelt

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2003

7

Inaktivierung von Parkin bei der Parkinson-Erkrankung

Konstanze F. Winklhofer

Journal:

Pharmazie in unserer Zeit

Année:

2006

Langue:

german

Fichier:

PDF, 278 KB

german, 2006

8

Protein immobilization on liposomes and lipid-coated nanoparticles by protein trans-splicing

Nam Ky Chu, Diana Olschewski, Ralf Seidel, Konstanze F. Winklhofer, Jörg Tatzelt, Martin Engelhard, Christian F. W. Becker

Journal:

Journal of Peptide Science

Année:

2010

Langue:

english

Fichier:

PDF, 284 KB

english, 2010

9

Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson’s disease

Anna Pilsl, Konstanze F. Winklhofer

Journal:

Acta Neuropathologica

Année:

2012

Langue:

english

Fichier:

PDF, 733 KB

english, 2012

10

Observing fibrillar assemblies on scrapie-infected cells

Susanne Wegmann, Margit Miesbauer, Konstanze F. Winklhofer, Jörg Tatzelt, Daniel J. Muller

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2008

Langue:

english

Fichier:

PDF, 561 KB

english, 2008

11

Misfolding of the Prion Protein at the Plasma Membrane Induces Endocytosis, Intracellular Retention and Degradation

Sophia Kiachopoulos, Johanna Heske, Jörg Tatzelt, Konstanze F. Winklhofer

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2004

12

Pathogenic mutations inactivate parkin by distinct mechanisms

Iris H. Henn, Johanna M. Gostner, Peter Lackner, Jörg Tatzelt, Konstanze F. Winklhofer

Journal:

Journal of Neurochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 466 KB

english, 2005

13

Stress-protective signalling of prion protein is corrupted by scrapie prions

Rambold, Angelika S, Müller, Veronika, Ron, Uri, Ben-Tal, Nir, Winklhofer, Konstanze F, Tatzelt, Jörg

Journal:

The EMBO Journal

Année:

2008

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2008

14

Human Cytomegalovirus Immediate-Early Gene 2 Expression Leads to JCV Replication in Nonpermissive Cells via Transcriptional Activation of JCV T Antigen

Konstanze F. Winklhofer, Ingrid Albrecht, Michael Wegner, Regine Heilbronn

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 373 KB

english, 2000

15

Parkinson's disease-associated genes and mitochondrial integrity

A. Kathrin Lutz, Anna Pilsl, Lena Bouman, Jörg Tatzelt, Konstanze F. Winklhofer

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2010

Langue:

english

Fichier:

PDF, 54 KB

english, 2010

16

Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb

Lisa Glasl, Karina Kloos, Florian Giesert, Anne Roethig, Barbara Di Benedetto, Ralf Kühn, Jingzhong Zhang, Ulrich Hafen, Julia Zerle, Andreas Hofmann, Martin Hrabé de Angelis, Konstanze F. Winklhofer,

Journal:

Experimental Neurology

Année:

2012

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2012

17

Mitochondrial dysfunction in Parkinson’s disease: molecular mechanisms and pathophysiological consequences

Exner, Nicole, Lutz, Anne Kathrin, Haass, Christian, Winklhofer, Konstanze F

Journal:

The EMBO Journal

Année:

2012

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2012

18

Mitochondrial dysfunction in Parkinson's disease

Konstanze F. Winklhofer, Christian Haass

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2010

Langue:

english

Fichier:

PDF, 693 KB

english, 2010

19

Prion protein-related proteins from zebrafish are complex glycosylated and contain a glycosylphosphatidylinositol anchor

Margit Miesbauer, Theresa Bamme, Constanze Riemer, Birgit Oidtmann, Konstanze F. Winklhofer, Michael Baier, Jörg Tatzelt

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 436 KB

english, 2006

20

A sensitive filter retention assay for the detection of PrPSc and the screening of anti-prion compounds

Konstanze F Winklhofer, F.Ulrich Hartl, Jörg Tatzelt

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 258 KB

english, 2001

21

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

Winklhofer, Konstanze F, Tatzelt, Jörg, Haass, Christian

Journal:

The EMBO Journal

Année:

2008

Langue:

english

Fichier:

PDF, 381 KB

english, 2008

22

Structural Instability of the Prion Protein upon M205S/R Mutations Revealed by Molecular Dynamics Simulations

Hirschberger, Thomas, Stork, Martina, Schropp, Bernhard, Winklhofer, Konstanze F., Tatzelt, Jörg, Tavan, Paul

Journal:

Biophysical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 623 KB

english, 2006

23

Cellular Prion Protein Mediates Toxic Signaling of Amyloid Beta

Resenberger, Ulrike K., Winklhofer, Konstanze F., Tatzelt, Jörg

Journal:

Neurodegenerative Diseases

Année:

2012

Langue:

english

Fichier:

PDF, 95 KB

english, 2012

24

Parkin and mitochondrial quality control: toward assembling the puzzle

Winklhofer, Konstanze F.

Journal:

Trends in Cell Biology

Année:

2014

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2014

25

Parkin — eine neuroprotektive E3-Ubiquitin-Ligase

Schnack, Cathrin, Berlemann, Lena, Winklhofer, Konstanze F.

Journal:

Année:

2014

Langue:

german

Fichier:

PDF, 453 KB

german, 2014

26

The polysaccharide scaffold of PrP 27-30 is a common compound of natural prions and consists of α-linked polyglucose

Dumpitak, Christian, Beekes, Michael, Weinmann, Nicole, Metzger, Sabine, Winklhofer, Konstanze F., Tatzelt, Jörg, Riesner, Detlev

Journal:

Biological Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 162 KB

english, 2005

27

The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity

Butler, Erin K., Voigt, Aaron, Lutz, A. Kathrin, Toegel, Jane P., Gerhardt, Ellen, Karsten, Peter, Falkenburger, Björn, Reinartz, Andrea, Winklhofer, Konstanze F., Schulz, Jörg B., Orr, Harry T.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2012

28

The mitochondrial kinase PINK1: functions beyond mitophagy

Voigt, Aaron, Berlemann, Lena A., Winklhofer, Konstanze F.

Journal:

Journal of Neurochemistry

Année:

2016

Langue:

english

Fichier:

PDF, 693 KB

english, 2016

29

PERK activation mitigates tau pathology in vitro and in vivo

Bruch, Julius, Xu, Hong, Rösler, Thomas W, De Andrade, Anderson, Kuhn, Peer‐Hendrik, Lichtenthaler, Stefan F, Arzberger, Thomas, Winklhofer, Konstanze F, Müller, Ulrich, Höglinger, Günter U

Journal:

EMBO Molecular Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2017

30

Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress

Menges, Stefanie, Minakaki, Georgia, Schaefer, Patrick M., Meixner, Holger, Prots, Iryna, Schlötzer-Schrehardt, Ursula, Friedland, Kristina, Winner, Beate, Outeiro, Tiago F., Winklhofer, Konstanze F.,

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 5.43 MB

english, 2017

31

The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins

Gonsberg, Anika, Jung, Sebastian, Ulbrich, Sarah, Origi, Andrea, Ziska, Anke, Baier, Michael, Koch, Hans-Georg, Zimmermann, Richard, Winklhofer, Konstanze F., Tatzelt, Jörg

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 9.91 MB

english, 2017

32

Increased ROS Level in Spinal Cord of Wobbler Mice due to Nmnat2 Downregulation

Röderer, Pascal, Klatt, Lara, John, Felix, Theis, Verena, Winklhofer, Konstanze F., Theiss, Carsten, Matschke, Veronika

Journal:

Molecular Neurobiology

Année:

2018

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2018

33

Parkin Is Protective against Proteotoxic Stress in a Transgenic Zebrafish Model

Fett, Mareike E., Pilsl, Anna, Paquet, Dominik, van Bebber, Frauke, Haass, Christian, Tatzelt, Jörg, Schmid, Bettina, Winklhofer, Konstanze F., Cookson, Mark R.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 3.52 MB

english, 2010

34

Neutrophil-generated HOCl leads to non-specific thiol oxidation in phagocytized bacteria

Degrossoli, Adriana, Müller, Alexandra, Xie, Kaibo, Schneider, Jannis F, Bader, Verian, Winklhofer, Konstanze F, Meyer, Andreas J, Leichert, Lars I

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 3.84 MB

english, 2018

35

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer’s disease

Ulbrich, Sarah, Janning, Petra, Seidel, Ralf, Matschke, Jakob, Gonsberg, Anika, Jung, Sebastian, Glatzel, Markus, Engelhard, Martin, Winklhofer, Konstanze F., Tatzelt, Jörg, Rezaei, Human

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2018

36

Mitochondria at the interface between neurodegeneration and neuroinflammation

Bader, Verian, Winklhofer, Konstanze F.

Journal:

Seminars in Cell & Developmental Biology

Année:

2019

Langue:

english

Fichier:

PDF, 822 KB

english, 2019

37

A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels

Teucher, Markus, Zhang, Hui, Bader, Verian, Winklhofer, Konstanze F., García-Sáez, Ana J., Rajca, Andrzej, Bleicken, Stephanie, Bordignon, Enrica

Journal:

Scientific Reports

Année:

2019

Langue:

english

Fichier:

PDF, 5.49 MB

english, 2019

38

A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels

Teucher, Markus, Zhang, Hui, Bader, Verian, Winklhofer, Konstanze F., García-Sáez, Ana J., Rajca, Andrzej, Bleicken, Stephanie, Bordignon, Enrica

Journal:

Scientific Reports

Année:

2019

Fichier:

PDF, 5.49 MB

2019

39

Activation leads to a significant shift in the intracellular redox homeostasis of neutrophil-like cells

Xie, Kaibo, Varatnitskaya, Marharyta, Maghnouj, Abdelouahid, Bader, Verian, Winklhofer, Konstanze F., Hahn, Stephan, Leichert, Lars I.

Journal:

Année:

2019

Fichier:

PDF, 3.07 MB

2019

40

Linear Ubiquitin Chains: Cellular Functions and Strategies for Detection and Quantification

Dittmar, Gunnar, Winklhofer, Konstanze F.

Journal:

Frontiers in Chemistry

Année:

2020

Langue:

english

Fichier:

PDF, 7.19 MB

english, 2020

41

SecY-mediated quality control prevents the translocation of non-gated porins

Jung, Sebastian, Bader, Verian, Natriashvili, Ana, Koch, Hans-Georg, Winklhofer, Konstanze F., Tatzelt, JÃ¶rg

Journal:

Scientific Reports

Année:

2020

Fichier:

PDF, 4.69 MB

2020

42

Protein quality control by the proteasome and autophagy: A regulatory role of ubiquitin and liquid-liquid phase separation

Lei, Linlin, Wu, Zhixiao, Winklhofer, Konstanze F.

Journal:

Année:

2020

Fichier:

PDF, 894 KB

2020